Publications by authors named "G Pooler Archbold"

Article Synopsis
  • Landscape fires are becoming more frequent and severe, significantly impacting public health and economies in places like Australia.
  • The Thoracic Society of Australia and New Zealand highlights that people with asthma, particularly vulnerable groups such as the elderly, pregnant women, and Indigenous peoples, are at higher risk from smoke exposure during these fires.
  • The position statement emphasizes the need for effective asthma management strategies, smoke mitigation, and increased awareness among clinicians and the general public about the dangers of landscape fire smoke.
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Unlabelled: The neurobiological processes underpinning the natural forgetting of long-term memories are poorly understood. Based on the critical role of GluA2-containing AMPA receptors (GluA2/AMPARs) in long-term memory persistence, we tested in rats whether their synaptic removal underpins time-dependent memory loss. We found that blocking GluA2/AMPAR removal with the interference peptides GluA23Y or G2CT in the dorsal hippocampus during a memory retention interval prevented the normal forgetting of established, long-term object location memories, but did not affect their acquisition.

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Memory retrieval is considered to have roles in memory enhancement. Recently, memory reconsolidation was suggested to reinforce or integrate new information into reactivated memory. Here, we show that reactivated inhibitory avoidance (IA) memory is enhanced through reconsolidation under conditions in which memory extinction is not induced.

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Evidence suggests that extinction is new learning. Memory acquisition involves both short-term memory (STM) and long-term memory (LTM) components; however, few studies have examined early phases of extinction retention. Retention of auditory fear extinction was examined at various time points.

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