Publications by authors named "G Plu-Bureau"

Article Synopsis
  • - Premature ovarian insufficiency (POI) is a condition where women's ovaries stop functioning normally before age 40, leading to infertility and hormonal issues, marked by absent menstrual cycles and high follicle-stimulating hormone levels.
  • - POI can be triggered by various factors, including medical treatments, genetic conditions, infections, and autoimmune diseases, affecting around 1 in 100 women, with a higher incidence before age 30.
  • - Recent advances in genetic research have improved our understanding of POI, allowing for better diagnosis and potential treatment options, including oocyte preservation for those with a family history of the condition.
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Aims: To evaluate the impact of onset time, duration, and severity of various types of hypertensive disorders of pregnancy (HDP) on the risk of incident DM.

Methods: We used data from the ongoing French nationwide prospective cohort study CONCEPTION. We included all primiparous women in CONCEPTION who delivered between 2010 and 2018 (n = 2,816,793 women).

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Background: Primary ovarian insufficiency (POI) affects around 2-4% of women before the age of 40. Genetic factors play an important role in POI. The GDF9 gene has been identified as a significant genetic contributor of POI.

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Background: We aimed to evaluate the impact of hypertensive disorders of pregnancy occurrence, recurrence, onset time, and severity on mortality and on a wide range of cardiovascular outcomes in France.

Methods And Results: CONCEPTION (Cohort of Cardiovascular Diseases in Pregnancy) is a French nationwide prospective cohort using data from the National Health Data System. We included all women in CONCEPTION with no history of a cardiovascular event who delivered in France for the first time between 2010 and 2018 (N=2 819 655).

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