Publications by authors named "G Pineiro-Corrales"
Article Synopsis
- Hepatocellular carcinoma, a leading cause of cancer deaths, is primarily treated with sorafenib, and this study evaluates its effectiveness and toxicity in real-world settings.
- A total of 36 patients were studied, revealing an average overall survival of 8.5 months and common adverse effects including constitutional, gastrointestinal, and dermatological issues.
- The results indicate that while survival outcomes in clinical practice align with clinical trials, the toxicity profile showed unexpected variations.
Background: Colorectal cancer is the ninth leading cause of death in Spain. The latest therapeutic developments in the advanced stages of this disease are the oral drugs trifluridine/tipiracil and regorafenib.
Objective: Results of clinical trials (CTs) are not in real conditions and therefore, we want to study the effectiveness and the safety profile in the usual clinical practice and compare it with the bibliography.
Backgound And Aims: Total parenteral nutrition (TPN) is an extremely complex mixture. The multitude of chemical compounds involved can give rise to numerous reactions that condition its stability. We set out to review the existing literature on different issues related to stability, and which are still of concern in the hospital environment; such as the stability of the lipid emulsion.
View Article and Find Full Text PDFPurpose: To evaluate the effectiveness, adverse reactions, and adherence to treatment of hypolipidemic inhibitors of proprotein convertase subtilisin/kexin type 9 (PCSK9is) in a context of real clinical practice.
Methods: We present an observational, retrospective, descriptive, multicenter study of patients with hypercholesterolemia who began treatment with PCSK9is between January 2017 and December 2019, with a minimum treatment period of 3 months. The main variable we recorded was the frequency of cardiovascular events (cardiovascular death, myocardial infarction, stroke, coronary revascularization, and hospitalization for unstable angina) in patients treated with PCSK9is.
Objective: The objective of this study was to assess the results of applying Lean Methodology in the design of a standardized medication storage model in hospitalization departments.
Method: Descriptive and retrospective study conducted between September 2017 and January 2019 in a tertiary level hospital. The Pharmacy Service led the creation of a multidisciplinary team.