Publications by authors named "G Pescia"
Understanding the real-time evolution of many-electron quantum systems is essential for studying dynamical properties in condensed matter, quantum chemistry, and complex materials, yet it poses a significant theoretical and computational challenge. Our work introduces a variational approach for fermionic time-dependent wave functions, surpassing mean-field approximations by accurately capturing many-body correlations. We employ time-dependent Jastrow factors and backflow transformations, enhanced through neural networks parameterizations.
View Article and Find Full Text PDFArticle Synopsis
- - Non-invasive prenatal testing (NIPT) is gaining popularity for its effectiveness in detecting fetal chromosomal issues, but it can also uncover unexpected health conditions in the mother.
- - A specific case showed that NIPT identified a chromosomal duplication in a fetus that raised concerns about Potocki-Lupski syndrome, but it turned out to be a hereditary condition from the mother, who has Charcot-Marie-Tooth neuropathy.
- - As NIPT expands to cover more genetic conditions, it's important for healthcare providers to prepare for the possibility of discovering maternal health issues during pre-test genetic counseling.
Purpose: Cell-free DNA (cfDNA) testing for fetal aneuploidies was broadly implemented for common trisomies and sex-chromosome anomalies (SCAs). However, such an approach identifies only 75 to 85% of clinically relevant aneuploidies.
Methods: We present a consecutive series of 6,388 cases, thus uncovering a broader array of aneuploidies, including the rare autosomal trisomies (RATs) and the maternally inherited deletion and duplication copy-number variations (CNVs), with complete and stratified follow-up by amniocentesis.
Background: The human infant accumulates body fat during intrauterine life. The guinea pig shares this characteristic and is born with similar adiposity; thus, it may be a relevant model to study obesity programming.
Objective: The objective of this study was to evaluate guinea pig adipose tissue (AT) development and the effect of a maternal high-fat diet on the offspring's body composition.