Effects of mud-bath treatment on fibromyalgia patients: a randomized clinical trial.

The efficacy of balneotherapy in fibromyalgia syndrome (FS) has been well demonstrated, while controlled studies using mud packs are lacking. We performed a randomized clinical trial to evaluate the effects and the tolerability of mud-bath treatment in FS patients, who are poor responders to pharmacological therapy. Eighty patients with primary FS, according to ACR criteria, were randomly allocated to two groups: 40 were submitted to a cycle of 12 mud packs and thermal baths, and 40 were considered as controls.

[Quality of life and associated clinical distress in fibromyalgia].

Objectives: Fibromyalgia (FM) is a syndrome characterized by chronic, diffuse musculoskeletal pain and by a low pain threshold at specific anatomical points (tender points). Numerous other conditions (Irritable bowel syndrome, tension-type headache, migraine headaches, etc.) may overlap with FM.

[Safety of lornoxicam in G-6-PDH deficiency].

Objective: To assess the safety of lornoxicam in subjects with G-6-PDH deficiency.

Methods: Open controlled 2-week in vivo study on lornoxicam 8 mg bid in subjects with G-6-PDH deficiency suffering from rheumatic diseases.

Results: In 8 male patients with the Mediterranean form of G-6-PDH deficiency (mean age +/- SD, 54.