Alcoholic liver disease represents a spectrum of liver injuries from fatty liver, steatohepatitis, fibrosis and cirrhosis to hepatocellular carcinoma. Progression of the disease depends on the amount of alcohol consumption and risk factors or comorbidities, e.g.
View Article and Find Full Text PDFLiver fibrosis is part of the structural and functional alterations in chronic liver diseases, and it is the most important prognostic factor of the risk of developing cirrhosis, liver-related complications and mortality. Although liver biopsy has traditionally been considered as the (gold standard) reference method for evaluation of fibrosis, owing to its invasiveness, sampling variability, and the static nature of information it yields, non-invasive fibrosis markers became alternatives for assessment of the severity and outcome of liver diseases during the last two decades. Serum biochemical tests, elastographies and imaging methods are available for the diagnosis and staging of fibrosis.
View Article and Find Full Text PDFBackground: Based on cross-sectional studies, there is a link between body composition parameters and steatosis in non-alcoholic fatty liver disease (NAFLD). However, whether long-term changes in different body composition parameters will result in NAFLD resolution is unclear. Therefore, we aimed to summarize the literature on longitudinal studies evaluating the association between NAFLD resolution and body composition change.
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