Publications by authors named "G Panneer Selvam"

Rare-earth-based nanomaterials with exceptional electrochemical properties can be obtained a simple, low-cost, environment-friendly citrate-gel-matrix approach. Owing to their high specific capacitance, strong conductivity, and electrochemical stability, gallium-based materials are capable of withstanding numerous charge-discharge cycles, thus extending the life cycle of a supercapacitor. This tunability enabled researchers to alter the morphology and composition of the electrode to enhance supercapacitor performance.

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Background: Chrysin (Chy) is a naturally occurring flavonoid found in fruits, vegetables, honey, propolis, and many plant extracts that has shown notable medicinal value. Chy exhibits diverse pharmacological properties, including anti-oxidative, anti-inflammatory, anti-apoptotic, anti-cholesteremic, and cardioprotective. However, the influence of Chy in mitigating high-fat diet (HFD)-induced ER stress of rat myocardium remains unknown.

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Background: Diabetic cardiomyopathy (DCM) is a form of cardiac dysfunction caused by diabetes, increasing heart failure and death. Studies shown that hyperglycemia-induced oxidative stress significantly affects heart structure and functional changes during diabetic cardiomyopathy. Fucoidans are sulfated polysaccharide derived from naturally available seaweeds and reported for various biological functions such as antioxidant, anti-diabetic, and anti-inflammatory.

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Article Synopsis
  • Haptoglobin (HP) is a protein that binds to free hemoglobin, protecting against iron loss and kidney damage, with genetic variations influencing health outcomes, specifically linked to chronic kidney disease (CKD) in different populations.
  • A study on a South Indian cohort involving 392 CKD patients and 202 healthy individuals found that the HP2-2 genotype significantly increased the risk of developing nondialysis CKD and end-stage renal disease (ESRD), indicating a higher frequency of this genotype relates to worse health outcomes.
  • The findings suggest the HP2-2 polymorphism is a strong independent predictor of CKD incidence, progression, and mortality, emphasizing its relevance for patient prognosis in the affected population.
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Chronic cadmium (Cd) exposure severely affects the structural integrity of the heart, leading to cardiovascular disease. This study investigates the protective role of ascorbic acid (AA) and resveratrol (Res) in cellular defense against Cd-induced cardiomyocyte damage and myocardial hypertrophy in H9c2 cardiomyocytes. Experimental results showed that AA and Res treatment significantly increased cell viability, reduced ROS production, attenuated lipid peroxidation, and increased antioxidant enzyme activity in Cd-induced H9c2 cells.

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