Pituitary Macroadenoma Presenting With Monocular Temporal Hemianopia.

A 35-year-old primigravida woman presented to the eye emergency department with reduced visual acuity in the right eye. Humphrey visual field testing showed a monocular right eye temporal hemianopia before delivery. An MRI after delivery revealed a largely symmetrical pituitary macroadenoma with chiasmal compression.

Ocular involvement in familial erythrophagocytic lymphohistiocytosis.

Background: Familial erythrophagocytic lymphohistiocytosis (FEL), a rare, rapidly fatal childhood disorder, is characterized by intermittent fevers, hepatosplenomegaly, cytopenia, hypercytokinemia and lymphohistiocytic infiltration with erythrophagocytosis involving multiple organs. We report the clinical and histological features of two infants with FEL and emphasize the ocular findings.

Methods: Microscopic examination of formalin-fixed, paraffin-embedded autopsy material was performed.

Diagnostic pars plana vitrectomy report of a 21-year retrospective study.

Purpose: To review the experience of diagnostic pars plana vitrectomies (PPV).

Methods: The authors reviewed 405 consecutive diagnostic PPV's performed between November 1973 and October 1994.

Results: Diagnostic vitrectomy was performed in 215 (53%) of 405 eyes for suspected endophthalmitis.

Herpes zoster ophthalmicus: an early pointer to HIV-1 positivity in young African patients.

We studied prospectively 30 patients, seen over 10 months, who had herpes zoster ophthalmicus (HZO) and who were classified by age, sex, ophthalmological observations and HIV-1 status. Of patients who presented with HZO, 40% were HIV positive, and the majority were less than 40 years of age. The clinical manifestation of HZO has a high positive predictive value for HIV positivity in young patients with this viral infection.

Ocular and systemic determination of IL-1 beta and tumour necrosis factor in a patient with ocular inflammation.

Cytokines such as interleukin-1 beta (IL-1 beta) and tumour necrosis factor (TNF) may play an important role in ocular inflammation. We studied a patient with clinical features of sympathetic ophthalmia secondary to previous penetrating ocular injuries, and compared the ocular and systemic levels of IL-1 beta and TNF to control serum, and correlated these findings to histopathological sections of the patient's eye. Histology showed the presence of a diffuse chronic inflammatory infiltrate within the choroid and in a perivascular distribution in the retina.