Publications by authors named "G Pal"

A significant area of computer science called artificial intelligence (AI) is successfully applied to the analysis of intricate biological data and the extraction of substantial associations from datasets for a variety of biomedical uses. AI has attracted significant interest in biomedical research due to its features: (i) better patient care through early diagnosis and detection; (ii) enhanced workflow; (iii) lowering medical errors; (v) lowering medical costs; (vi) reducing morbidity and mortality; (vii) enhancing performance; (viii) enhancing precision; and (ix) time efficiency. Quantitative metrics are crucial for evaluating AI implementations, providing insights, enabling informed decisions, and measuring the impact of AI-driven initiatives, thereby enhancing transparency, accountability, and overall impact.

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  • The study investigates how subthalamic nucleus deep brain stimulation (STN-DBS) surgery affects cognitive aspects of motor control in people with Parkinson's disease (PD) over time.
  • Researchers compared participants' saccade latency and reach reaction time before surgery and about 8 months after surgery while off medication and stimulation.
  • Results showed that both saccade latency and reach reaction time significantly worsened post-surgery, suggesting negative long-term cognitive impacts from the surgery.
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  • Schistosomes are skilled at evading human immunity, particularly the complement system, allowing them to survive in human blood for years; this study explores how they interact with this immune response.
  • The research shows that newly formed schistosomula are initially very vulnerable to complement attack, but they can rapidly boost their survival rate, especially when they recruit complement regulator factor H to avoid destruction.
  • The use of the drug praziquantel increases the susceptibility of schistosomula to complement-mediated killing, suggesting that further investigation into factor H's role could help develop new treatments against schistosomes.
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Background: Anxiety disorders are commonly associated with a higher risk of fatal cardiovascular diseases (CVD). Anxiety disorders lead to dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis, thus weakening the key neuronal components of the autonomic nervous system (ANS) that are involved in cardiovascular functions, leading to increased cardiovascular risk.

Purpose: Impaired ANS activity, as reduced parasympathetic tone is strongly associated with an increased risk of CVD in anxiety disorders.

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Objective: There is conflicting evidence whether decreased clerkship duration is associated with reduced NBME shelf examination performance. We hypothesized that scores would remain stable for students in a shortened 2-week flipped classroom-based virtual rotation as compared to the traditional 4-week Neurology clerkship.

Background: There is conflicting evidence whether decreased clerkship duration is associated with reduced NBME shelf examination performance.

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