Publications by authors named "G Paganetto"

Since ancient times, mushrooms have been considered valuable allies of human well-being both from a dietary and medicinal point of view. Their essential role in several traditional medicines is explained today by the discovery of the plethora of biomolecules that have shown proven efficacy for treating various diseases, including cancer. Numerous studies have already been conducted to explore the antitumoural properties of mushroom extracts against cancer.

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(CP) is a common Indian herb, largely employed in Ayurvedic medicine and known for its neuroprotective and neuroinflammatory action. Its effectiveness against several pathologic/sub-pathologic conditions is widely accepted, but it is not yet completely chemically characterized. In recent years, several researchers have pointed out the involvement of CP and other Convolvulaceae in lipidic and glucidic metabolism, particularly in the control of hyperlipidaemia and diabetic conditions.

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Ferroptosis induction is an emerging strategy to treat cancer and contrast the tricky issue of chemoresistance, which can arise towards apoptosis. This work elucidates the anticancer mechanisms evoked by perillaldehyde, a monoterpenoid isolated from Ammodaucus leucotrichus Coss. & Dur.

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Essential oils (EOs) and their vapour phase of (Zingiberaceae), (Poaceae), (Lamiaceae), and (Zingiberaceae) of cultivated plants grown in an Amazonian Ecuador area were chemically characterised by Gas Chromatography-Flame Ionization Detector (GC-FID), Gas Chromatography-Mass Spectrometry (GC-MS), and Head Space-Gas Chromatograph-Flame Ionization Detector-Mass Spectrometry (HS-GC-FID-MS).figure The EOs analyses led to the identification of 25 compounds for (99.46% of the total; ar-turmerone: 23.

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Article Synopsis
  • - Three specimens of a plant subspecies were collected in Italy's Abruzzo region for botanical identification and analysis of their essential oils, revealing three distinct chemotypes, including a new one characterized by high levels of (-)-limonen-10-yl-acetate.
  • - Despite concerns about genotoxicity from related compounds reported by the EFSA in 2017, tests indicated that the new chemotype (CIV17-EO) showed no mutagenic activity, supporting its safety for use as a flavoring substance.
  • - The ethanolic extracts of the plants contained beneficial compounds like caftaric, chlorogenic, and rosmarinic acid, demonstrating significant antioxidant activity and slight cytotoxicity against the A549
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