Publications by authors named "G Padron"
Article Synopsis
- Real-world organisms face multiple stressors simultaneously, but lab studies usually focus on single stressors in simplified conditions.
- This study uses microfluidics to apply both physical (shear flow) and chemical (hydrogen peroxide) stressors to the bacteria Pseudomonas aeruginosa, revealing that flow significantly enhances the effectiveness of HO on bacterial growth.
- The findings show that natural levels of these stressors interact in ways that limit bacterial movement and survival, emphasizing the importance of studying multiple stressors to better understand their true effects.
Article Synopsis
- Laboratory studies often focus on single stressors, while in nature, organisms face multiple stressors at once.
- This research used a microfluidic approach to combine physical (shear flow) and chemical (H2O2) stressors on a human pathogen, revealing that flow greatly enhances the effectiveness of H2O2 against bacteria.
- Findings indicate that natural levels of H2O2 and flow work together to impede bacterial growth, suggesting that studying multiple stressors is crucial for understanding real-life biological interactions.
Article Synopsis
- * Researchers utilized biophysical simulations and microfluidic experiments, finding that increased fluid flow helps overcome bacterial resistance to various antimicrobials by enhancing their delivery.
- * The study highlights the importance of combining physical flow with chemical dosage in developing effective antimicrobials, suggesting that this strategy could be crucial in combating rising antimicrobial resistance.
The protein map of the protozoan parasite Leishmania (Leishmania) amazonensis, Leishmania (Viannia) braziliensis and Leishmania (Leishmania) infantum during growth phase transition and temperature stress.
J Proteomics
March 2024
Leishmania parasites cause a spectrum of diseases termed leishmaniasis, which manifests in two main clinical forms, cutaneous and visceral leishmaniasis. Leishmania promastigotes transit from proliferative exponential to quiescent stationary phases inside the insect vector, a relevant step that recapitulates early molecular events of metacyclogenesis. During the insect blood meal of the mammalian hosts, the released parasites interact initially with the skin, an event marked by temperature changes.
View Article and Find Full Text PDFObjective: To analyze the perspectives and practices of personnel involved in family planning with women at reproductive risk due to chronic diseases.
Method: Qualitative study in which physicians and nurses from primary care centers in a state in central Mexico were interviewed. Interviews were transcribed and analyzed under the Grounded Theory proposal.