Publications by authors named "G P Vaudano"
Purpose: Acute ischemic stroke is currently among the main causes of mortality in Western countries. The current guidelines suggest different flowcharts of diagnostic work-up and treatment modalities, including endovascular thrombectomy. Immediately after intra-arterial recanalization, a brain CT scan is usually performed to assess for the presence of peri-procedural complications; in this setting, it is very hard, if possible, to differentiate blood from iodinated contrast material, which is normally present in ischemic tissue because of BBB disruption.
View Article and Find Full Text PDFArticle Synopsis
- This study explores the effectiveness of a Convolutional Neural Network (CNN) in creating parametric maps from CT perfusion data in patients with acute ischemic stroke.
- The CNN was trained on 100 pre-processed datasets, and its performance was assessed by comparison with ground truth maps generated by a deconvolution algorithm, showing high accuracy and strong inter-rater agreement.
- The results indicate that CNN-based perfusion maps can accurately reflect ischemic areas, suggesting promising advancements in machine learning applications for medical imaging and analysis.*
Acute necrotising pancreatitis (ANP) is associated with high complication and mortality rates. It is still difficult for the surgeon to choose and schedule the most appropriate treatment. Compared to the past, the current minimally invasive "step-up" approach enables better outcomes in terms of morbidity/mortality, notwithstanding long periods of hospitalisation, and above all ensures better levels of residual pancreatic function.
View Article and Find Full Text PDFBilateral simultaneous middle cerebral artery occlusion is a rare condition that may lead to severe neurological disability or death, thus requiring rapid intervention in order to restore vessels patency and brain perfusion. Perfusion-computed tomography is demonstrated to be a fundamental tool for selecting stroke patients candidate to mechanical thrombectomy, but its role for guiding the optimal strategy of endovascular treatment in concomitant multivessel cerebral occlusion has never been reported. We describe a case of bilateral middle cerebral artery occlusion in which perfusion-computed tomography was crucial both for addressing to endovascular procedure and planning the sequence treatment of mechanical thrombectomies.
View Article and Find Full Text PDFIntroduction: An ancillary advantage of bioresorbable scaffolds is the possibility of non-invasive imaging assessment of the treated coronary segment. Cardiac computed tomography angiography (CCTA) studies of resorbable magnesium scaffolds (RMS) are scarce.
Methods: In this collaborative, international study, nine patients who had an RMS implanted underwent CCTA as part of follow-up assessment.