Publications by authors named "G P Petrelli"
Background And Objectives: The European Medicine Agency extended the use of Comirnaty, Spikevax, and Nuvaxovid in paediatrics; thus, these vaccines require additional real-world safety evidence. Herein, we aimed to monitor the safety of COVID-19 vaccines through Covid-19 Vaccine Monitor (CVM) and EudraVigilance surveillance systems and the published pivotal clinical trials.
Methods: In a prospective cohort of vaccinees aged between 5 and 17 years, we measured the frequency of commonly reported (local/systemic solicited) and serious adverse drug events (ADRs) following the first and second doses of COVID-19 vaccines in Europe using data from the CVM cohort until April 2022.
Article Synopsis
- Conventional vaccines are generally safe with mild allergic reactions, but mRNA-based COVID-19 vaccines showed higher risks of severe allergies compared to standard vaccines.
- A literature review was conducted to examine the frequency, risk factors, and mechanisms of allergic reactions related to COVID-19 vaccines, using MEDLINE, Google Scholar, and other databases for data analysis.
- The study also compiled recommendations from scientific societies and regulatory agencies for preventing and managing allergic reactions to COVID-19 vaccines, particularly for individuals with previous allergies.
The COVID-19 pandemic widely disrupted the delivery of healthcare services, including genetic counseling. To ensure continuity of care, the reproductive genetic counselors at a large academic medical center in the United States rapidly transitioned their practice from 90% in-person patient consultations to a predominantly telehealth model. The present study describes this transition in regard to patient access to genetic counseling and genetic screening.
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- Surgical extrusion is a method to help fix teeth that are damaged but still have a good shape and strong roots.
- The process is easy and can be done quickly by a dentist.
- An example is given where this method was used to save a back tooth that had lost a lot of its structure but still had healthy supporting tissue.
A real life evaluation of non invasive ventilation in acute cardiogenic pulmonary edema: a multicenter, perspective, observational study for the ACPE SIMEU study group.
BMC Emerg Med
December 2018
Background: During the past three decades conflicting evidences have been published on the use of non-invasive ventilation (NIV) in patients with acute cardiogenic pulmonary edema (ACPE). The aim of this study is to describe the management of acute respiratory failure (ARF) due to ACPE in twelve Italian emergency departments (EDs). We evaluated prevalence, characteristics and outcomes of ACPE patients treated with oxygen therapy, continuous positive airway pressure (CPAP) or Bi-level positive airway pressure (BiPAP) on admission to the EDs.
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