Publications by authors named "G P MAZZOLENI"
Sewage sludge (biosolids) management represents a worldwide issue. Due to its valuable properties, approximately one half of the EU production is recovered in agriculture. Nevertheless, growing attention is given to potential negative effects deriving from the presence of harmful pollutants.
View Article and Find Full Text PDFThe descriptive epidemiology of melanoma in Italy has changed - for the better.
Ital J Dermatol Venerol
December 2023
A recent research project using data from a total of 40 cancer registries has provided new epidemiologic insights into the results of efforts for melanoma control in Italy between the 1990s and the last decade. In this article, the authors present a summary and a commentary of their findings. Incidence increased significantly throughout the study period in both sexes.
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- - The study investigates the prevalence and trends of pregnancy-associated cancer (PAC) in Italy, highlighting the growing concern as more women delay childbirth.
- - Utilizing data from 19 cancer registries covering 22% of the population, the research analyzed over 2.8 million pregnancies, identifying 3,559 cases of PAC with breast, thyroid, and melanoma cancers being the most common types.
- - Findings indicate a rising trend of PAC from 2003 to 2015, with 53.1% of cases resulting in delivery, emphasizing a shift in clinical practices for managing cancer during pregnancy, providing crucial insights for healthcare providers.
The process of identifying and approving a new drug is a time-consuming and expensive procedure. One of the biggest issues to overcome is the risk of hepatotoxicity, which is one of the main reasons for drug withdrawal from the market. While animal models are the gold standard in preclinical drug testing, the translation of results into therapeutic intervention is often ambiguous due to interspecies differences in hepatic metabolism.
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- The study investigates survival trends in vulvar squamous cell carcinoma (VSCC) in Italy from 1990 to 2015, revealing stagnation in survival rates.
- Analysis of data from 38 cancer registries indicated a decrease in 1-year and 2-year net survival rates, while 5-year conditional survival showed a slight increase but was not statistically significant.
- The findings suggest that current treatment and control strategies for VSCC need to be re-evaluated in Italy and worldwide due to the lack of improvement in survival outcomes.