Publications by authors named "G P Lewis"
Background And Aims: Individuals with steatotic liver disease (SLD) are at high cardiovascular disease (CVD) risk, but approaches to characterise and mitigate this risk are limited. By investigating relations, and shared metabolic pathways, of hepatic steatosis/fibrosis and cardiorespiratory fitness (CRF), we sought to identify new avenues for CVD risk reduction in SLD.
Methods: In Framingham Heart Study (FHS) participants (N = 2722, age 54 ± 9 years, 53% women), vibration-controlled transient elastography (VCTE) was performed between 2016-2019 to assess hepatic steatosis (continuous attenuation parameter [CAP]) and fibrosis (liver fibrosis measure [LSM]).
The incidence of infections attributed to antimicrobial-resistant (AMR) pathogens has increased exponentially over the recent decades reaching 1.27 million deaths worldwide in 2019. Without intervention, these infections are predicted to cause up to 10 million deaths a year and incur costs of up to 100 trillion US dollars globally by 2050.
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- The study evaluated the effectiveness of interdisciplinary pain management programs (IPMPs) for complex regional pain syndrome (CRPS) compared to low back pain (LBP) and chronic widespread pain (CWP).
- Researchers found that recovery trajectories for pain interference and pain intensity were similar across CRPS, LBP, and CWP patients, indicating equivalent benefits from IPMPs.
- Machine learning models were successfully used to predict recovery outcomes based on initial characteristics, classifying 69% for pain interference and 88% for pain intensity recovery trajectories.
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- Breast cancer is the most common cancer worldwide, and while the survival rate is high in the U.S., many survivors experience significant stress, anxiety, and depression due to unmet supportive care needs.
- This study aimed to create a mobile health app called MOSAIC, focusing on acceptance and commitment therapy (ACT) strategies to support breast cancer survivors.
- Through five user-centered design sessions with survivors and experts, key features for the app were identified, including user-friendly navigation, skill-building exercises, and social support elements to enhance the experience for users.
Livestock can contribute fecal indicator bacteria (FIB) to waterbodies. However, few studies have examined the relationship between watershed land use or land cover involving livestock production and the genetic diversity of Escherichia coli in freshwater ecosystems. Our major goal was to determine if FIB abundance and E.
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