Publications by authors named "G P Kouraklis"
: There is a growing interest in the research of wound healing mechanisms worldwide. Particular attention has been paid to the expression of tissue remodeling- and inflammation-related factors. Herein, we investigate the expression patterns of TGF-β1, IL-6, TNF-a, uPA, uPA receptors, MMP-2, and MMP-9 through the four phases of the normal wound-healing process in humans.
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- Triple negative breast cancer is one of the most aggressive types, and HDAC-2 enzymes play a significant role in its development and progression.
- A study examined 138 breast cancer samples to analyze the relationship between HDAC-2 levels and patient survival and disease features.
- Findings indicated that high HDAC-2 expression in triple negative cases is linked to better overall and disease-free survival compared to non-triple negative cases.
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- Pancreatic neuroendocrine tumors (PNETs) are classified into functioning and non-functioning types, with non-functioning tumors being the most common and associated with higher morbidity due to potential tissue invasion and metastasis.
- Insulinoma is the most prevalent functioning PNET, leading to symptoms from excess insulin, while glucagonoma is another type that causes hyperglycemia from high glucagon levels, and the co-occurrence of both is extremely rare.
- A literature review identified 8 cases of patients with both insulinoma and glucagonoma from 1992 to 2021, highlighting the need for a multidisciplinary approach for effective diagnosis and treatment.
Background/aim: Liver cancer constitutes one of the leading cancers globally. During pregnancy, however, liver cancer is an absolute rarity, with very few cases reported in the international literature. The aim of the present review was to provide a useful update and summarize all case studies of liver cancer in pregnancy published between 2012-2023.
View Article and Find Full Text PDFEndometrial cancer and uterine sarcoma represent the two major types of uterine cancer. In advanced stages, both cancer entities are challenging to treat and correlate with a meagre survival and prognosis. Hyperthermic Intraperitoneal Chemotherapy (HIPEC) is a form of localized chemotherapy that is heated to improve the chemotherapeutic effect on peritoneal metastases.
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