Publications by authors named "G P Girginov"

The phagocytic activity was studied of 421 poulets and cocks of lines 66 and 77 of the Cornish breed, and lines 88 and 99 of the White Plymouth rock breed. Breed and linear differences were noticed in the changes of the phagocytic activity (phagocytic number and phagocytic index) with birds infected with the virus of Marek's disease. The rise of the phagocytic activity with lines 66 and 77 was slighter as compared with that of the White Plymouth Rock lines 88 and 99.

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Studied was the polymorphism of alkaline phosphatase in blood plasma samples taken from 507 poulets and cocks of lines 66 and 77 of the Cornish breed, and lines 88 and 99 of the White Plymouth Rock breed. The birds were divided into three groups to test their resistance to Marek's disease: (1) controls, (2) infected with the virus of Marek's disease with 3 subgroups--resistant birds, slightly susceptible ones, and strongly susceptible ones, and (3) contacts, with two subgroups--survivals and birds that died. The blood plasma alkaline phosphatase was determined through horizontal electrophoresis on a starch gel, employing the method of Gahne.

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Studied was the resistance, resp., susceptibility of the initial broiler lines - 66 and 77 of the Cornish breed, and 88 and 99 of the Plymouth Rhock breed, which are used in this country for the production of the four-line hybrid, - to the virus of the Marek's disease, isolate CT-1. A biologic assay was carried out with a total of 2080 young birds divided into three groups; I groups - infected abdominally; II group - contacts; and III group - controls.

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An inactivated saponine vaccine is prepared from five highly immunogenic Salmonella abortus ovis strains, selected by means of a biological test on white rats. Saline was used as a diluent of the vaccine, with the addition of 30 per cent glycerine, 0.012 per cent saponine and 0.

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Furazolidon given alone or in combination with chloramphenicol, with spectinomycin, with gentamycin or with sodium arsenilate as well as chlorpyrazine, applied alone, suppress the clinical manifestation of pullorum disease in birds both in the experimental and in the spontaneous outbreak of the disease. These medicinal drugs lower the production of agglutinins in birds--mostly the combination furazolidon+chloramphenicol, followed by furazolidon+sodium arsenilate. The same combinations do not prove essentially effective in influencing the development of the morphologic lesions and do not fully exempt the body from the causative agent of pullorum disease.

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