Publications by authors named "G P Borkowski"
Article Synopsis
- Ischemic acute kidney injury (AKI) is a frequent issue for hospitalized patients and increases the risk of developing chronic kidney disease (CKD).
- The study identifies the importance of specific enzymes (PHD1, PHD2, and PHD3) in kidney repair after ischemia, revealing that altering these enzymes leads to worse kidney damage and inflammation.
- Inhibiting a protein called MCT4 can improve kidney repair by reducing inflammation and preventing damage caused by a faulty metabolic response in endothelial cells, suggesting a potential treatment strategy for preventing the progression from AKI to CKD.
Article Synopsis
- Ischemic acute kidney injury (AKI) is a common issue in hospitalized patients that can lead to chronic kidney disease (CKD), with endothelial cell dysfunction playing a significant role in this transition.
- Researchers found that enzymes called prolyl hydroxylase domain (PHD) 1-3 are crucial for kidney repair after ischemia, and their inactivation worsens tissue injury and inflammation.
- Inhibiting a specific transporter (MCT4) associated with this process improved kidney repair in mice, suggesting a potential therapeutic approach to prevent the progression from AKI to CKD.
In this study, composites containing polylactide and carbonate lake sediment in concentrations of 2.5, 5, 10, and 15% by weight were prepared by a 3D printing method. The material for 3D printing was obtained by directly diluting the masterbatch on an injection moulder to the desired concentrations, and after granulation, it was extruded into a filament.
View Article and Find Full Text PDFPurpose: Many practices have implemented support services to assist radiologists with noninterpretive tasks; however, little research has been performed to assess the overall effect of these services. The purpose of this study was to evaluate the effect of a team of imaging service navigators (ISNs) incorporated into a practice on (1) number of communications, (2) time saved by radiologists, and (3) radiologist satisfaction with the service.
Methods: The numbers and types of reports dictated by radiologists were captured for 6-month periods before and after ISN implementation.
In this study, the influence of carbonate lake sediments (Polylactide/Carbonate Lake Sediments-PLA/CLS) on the mechanical and structural properties of polylactide matrix composites was investigated. Two fractions of sediments originating from 3-8 and 8-12 m were analysed for differences in particle size by distribution (Dynamic Light Scattering-DLS), phase composition (X-ray Diffraction-XRD), the presence of surface functional groups (Fourier Transform-Infrared-FT-IR), and thermal stability (Thermogravimetric Analysis-TGA). Microscopic observations of the composite fractures were also performed.
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