Inborn Errors of Immunity: New Insights.

This paper presents a comprehensive and updated overview of inborn errors of immunity (IEIs), focusing on the optimal treatment strategies. IEIs or primary immunodeficiencies (PIDs) are a heterogeneous group of approximately 500 disorders, classified into ten categories according to the affected component of the immune system. The clinical presentation varies, based on the type of the disorder and the patient's age.

Awareness of deficit following traumatic brain injury: A systematic review of current methods of assessment.

Awareness of deficit plays an important role in adjustment following a brain injury and has been noted to impact on engagement with and outcome of rehabilitation. However, there are challenges associated with the assessment of awareness. To systematically review all instruments used to assess intellectual awareness of deficits following Traumatic Brain Injury (TBI) in adults, and evaluate instrument characteristics (e.

Thinking about other's mistakes: contrasting patterns of performance in groups high or low in autistic or psychopathic traits.

Counterfactual thinking refers to thoughts such as, "What if … ?" or "If only … " that hypothesise about how past events might have turned out differently. It is a functional process, allowing us to reflect upon and solve problems, and to evoke appropriate responses. It is thought to involve both cognitive and emotional processes, and is linked to the development of false belief and moral emotions.

Pediatric traumatic brain injury and antisocial behavior: are they linked? A systematic review.

: Despite growing evidence supporting a link between pediatric traumatic brain injury (TBI) and antisocial behavior, little work has rigorously evaluated this. This review aimed to explore systematically previous literature on the association between TBI before the age of 19 and severe behavioral problems such as violence, aggression and assault. : All articles published from 1990 to 2018 were searched using four major databases, alongside manual searching and cross-referencing.

Derailing the trolley: Everyday utilitarian judgments in groups high versus low in psychopathic traits or autistic traits.

Moral decision-making has been linked with empathy. The present study built on previous work examining the relationship between psychopathy or autism spectrum disorder (ASD), two conditions putatively associated with deficits in empathy, and utilitarian decision-making. Students scoring high on self-report measures of psychopathic or autistic traits were presented with a novel task, 'Utilitarian Judgments', and compared to low trait control groups.