Revealing inducible clindamycin resistance in methicillin-resistant S aureus : A vital diagnostic imperative for effective treatment.

Introduction: The World Health Organization added methicillin-resistant S aureus (MRSA) to the list of "priority pathogens," given its capacity to cause life-threatening infections. Clindamycin is a preferred treatment for non-complicated S aureus-induced skin and soft tissue infections. Its good tissue penetration and oral absorption make it suitable for outpatient therapy.

Optical parametric amplification and oscillation in nonlinear chiral media.

We discuss the nonlinear process of optical parametric amplification inside a chiral crystal. We show that circular birefringence, induced by chirality, leads to two different nonlinear processes with different phase-matching conditions that are associated with the opposite states of circular polarizations. A single nonlinear process occurs only when the states of polarization of the incident pump and signal beams are both circular and orthogonal.

Osteogenic citric acid linked chitosan coating of 3D-printed PLA scaffolds for preventing implant-associated infections.

>25 % of the patients who receive orthopedic implants have been reported with implant-associated osteomyelitis, which can result in inflammation, osteolysis, and aseptic loosening of implants. Current treatment methods doesn't ensure defect healing and prevention from reinfection. Thermoplastic-based 3D-printed scaffolds offer a bioresorbable, biocompatible, and mechanical strong implant system.