Reproducibility of histopathologic diagnosis and classification of non-melanocytic skin cancer: a panel exercise in the framework of the multicenter southern European study HELIOS.

Aims And Background: The reproducibility of histologic diagnoses, and in particular of the distinction between basal and squamous cell forms, has been evaluated in the framework of a multicenter case-control study (in Italy, France, Spain and Switzerland) aimed to assess the causes of non-melanocytic skin cancers.

Methods: A panel composed of 10 pathologists from the collaborating centers was appointed. A total of 1,774 slides of routine diagnoses were blindly reviewed by a second panelist; discordant diagnoses underwent a third examination.

Microscopic rice bodies in rheumatoid synovial fluid sediments.

To determine the clinical significance of the microscopic study of the synovial fluid (SF) sediment, 306 sediments were examined from 216 patients with the most frequently occurring acute and chronic arthropathies. The SF was obtained using a fine gauge needle. Microscopic rice bodies were seen in 53 (17.

[Cholelithiasis and cancer: a study using precursor changes in a population with low incidence of cholelithiasis].

In order to assess the role of cholelithiasis in the pathogenesis of gallbladder carcinoma in a low-risk population for cholelithiasis and gallbladder cancer, we have studied the relationship between cholelithiasis and cancer. Our findings suggest that, both the relationship between cancer and cholelithiasis, and the frequency of precursors lesions, are very similar to those obtained in surveys carried out in high-risk populations for both conditions. Our findings bear out our hypothesis that cholelithiasis plays a main role in the pathogenesis of gallbladder carcinoma.

[Cholelithiasis in the region of Cartagena: an approximation to its real incidence based on the study of its symptomatic group].

We have studied the frequency of cholelithiasis in a group of patients who complained of clinical symptoms of cholelithiasis and lived in the region of Cartagena. This group of patients accounts for 40% of all the patients suffering from cholelithiasis this would account for 0.5% of the whole population and 1% of the exposed population over 30 year-of-age.

[The so-called appendiceal mucocele versus mucinous cystadenoma].

In a review of 3,573 appendectomies, three diagnoses of mucinous cystadenoma of the cecal appendix and eleven cases of appendicular mucocele were encountered. Once the new divisions were made and the pictures were reclassified, we found simple mucocele on only 3 occasions, the other 8 corresponding to mucinous cystadenomas. Appendicular mucocele requires serial microscopic study in which the papillary proliferative or mucosecretory lesions, although minimal, are evaluated as cystadenoma lesions.