Publications by authors named "G Ortiz-Luna"

In postmenopausal women, due to endocrine changes, there is an increase in oxidative stress (OS) that predisposes them to cardiovascular and metabolic alterations. Sixty-one percent of women in this stage require a primary therapeutic strategy to decrease OS. This study aimed to evaluate the effect of resveratrol and vitamin C on OS in postmenopausal women.

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Background: Age-adjusted rates of cardiovascular disease (CVD) are higher in men than in women. CVD risk-factor outcomes are underrecognized, underestimated, and undertreated in women because the clinical expressions in women differ from those of men. There are no universally accepted recommendations on what to do in women when the values of fasting glucose, blood pressure, and lipids are only slightly altered or at borderline values.

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During the postmenopausal period, there are metabolic alterations that predispose individuals to metabolic syndrome (MS), oxidative stress (OS), and the risk of developing cardiovascular diseases. We aimed to compare the concentrations of OS markers in postmenopausal women with and without MS. Malondialdehyde, carbonyl groups, and total antioxidant capacity (TAC) were quantified.

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In the reproductive phase, women experience cyclic changes in the ovaries and uterus, and hormones regulate these changes. Menopause is the permanent loss of menstruation after 12 months of amenorrhea. Menopause is also linked to a decrease in estrogen production, causing an imbalance in oxidative stress.

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Article Synopsis
  • The study analyzed 217 Mexican participants across six groups of glucose tolerance, including healthy controls and various stages of Type 2 Diabetes (T2D), to examine differences in gut microbiota diversity.
  • Key findings revealed that the gut microbiota of individuals with T2D not on medication had lower richness and diversity compared to other groups, with significant variations in microbial composition between all groups.
  • The researchers identified specific gut bacteria linked to clinical parameters and predicted metabolic pathways for each condition, suggesting potential dietary and probiotic interventions to improve glucose tolerance in people with prediabetes or T2D.
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