Effect of Obesity on Resistin Concentrations in Normal, Pre-Obese and Obese Apparently Healthy Nigerian-Africans.

Background: Among Caucasians, conflicting findings exist on resistin in obesity and its relation to metabolic indices, with scarcity of such in Nigerian-Africans. Therefore, the study assessed plasma resistin and explored its relationship with obesity and selected cardiometabolic risks.

Methods: A cross-sectional comparative-analytical study on 87 randomly-selected non-diabetic Nigerians allocated into three groups by the WHO criteria: 24 normal; 23 pre-obese and 40 obese.

Leptin Concentrations in Non-Obese and Obese Non-Diabetes Nigerian-Africans.

Background: Controversial findings exist on the role of leptin in obesity and its correlation with metabolic variables, with few data emanating from Nigerian-Africans. Plasma leptin was therefore determined in obese and non-obese. Its relationship with obesity indices and metabolic variables were further envisaged.

Leptin concentrations in type 2 diabetes and non-diabetes Nigerian-Africans.

Most studies on leptin in diabetes mellitus (DM) compared to healthy controls were done in Caucasians, with conflicting findings. Paucity of data on this exists in Nigerian-Africans. Therefore, the study determined plasma leptin concentrations in newly diagnosed type-2 diabetes versus controls and its relation to obesity/demographic-metabolic indices.

Cardiovascular risk factors in adult general out-patient clinics in Nigeria: a country analysis of the Africa and Middle East Cardiovascular Epidemiological (ACE) study.

Background: With globalization and rapid urbanization, demographic and epidemiologic transitions have become important determinants for the emergence of cardiovascular disease (CVD).

Objective: To estimate the prevalence of CVD risk factors in adult out-patients attending general practice and non-specialist clinics in urban and rural Nigeria.

Methods: As part of the Africa and Middle East Cardiovascular Epidemiological (ACE) study, a cross-sectional epidemiologic study was undertaken for the presence of hypertension, diabetes mellitus, dyslipidemia, obesity, smoking and abdominal obesity in Nigeria.

Cerebral atrophy and dementia in type 2 diabetes mellitus: report of two cases and review of literature.

A report of two cases of cerebral atrophy and dementia possibly arising as a result of poor control of type 2 Diabetes Mellitus are presented The two elderly patients presented to the old age Psychiatric clinic with history of impairment in memory and changes in personality. They had a history of long standing poorly controlled diabetes mellitus. They were assessed using psychometric instruments, laboratory investigation and neuro-imaging.