Analytical solutions and Herzberg's energy level for modified shifted morse molecular system.

The solution of the radial Schrödinger equation for the modified shifted Morse potential model is obtained using an approximate supersymmetric approach. The two different formulae for the computation of the centrifugal distortion constant are clearly examined to deduce the formula that gives the result that perfectly aligns with the experimental data. Numerical values for different molecules are computed for the two different values of the centrifugal distortion constant (dissociation energy) obtained from two different equations.

Non-relativistic molecular modified shifted Morse potential system.

A shifted Morse potential model is modified to fit the study of the vibrational energies of some molecules. Using a traditional technique/methodology, the vibrational energy and the un-normalized radial wave functions were calculated for the modified shifted Morse potential model. The condition that fits the modified potential for molecular description were deduced together with the expression for the screening parameter.

Experimental validation and molecular docking to explore the active components of cannabis in testicular function and sperm quality modulations in rats.

Background: Data available support that ninety percent of male infertility cases are due to low sperm counts. There is a scarcity of data on the medicinal effects of cannabis on fertility. This study evaluated testicular function and sperm quality modulation with cannabis in rats.

Synthesis and characterization of novel combretastatin analogues of 1,1-diaryl vinyl sulfones, with antiproliferative potential via in-silico and in-vitro studies.

Novel 1,1-diaryl vinyl-sulfones analogues of combretastatin CA-4 were synthesized via Suzuki-Miyaura coupling method and screened for in-vitro antiproliferative activity against four human cancer cell lines: MDA-MB 231(breast cancer), HeLa (cervical cancer), A549 (lung cancer), and IMR-32 (neuroblast cancer), along with a normal cell line HEK-293 (human embryonic kidney cell) by employing 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide (MTT) assay. The compounds synthesised had better cytotoxicity against the A549 and IMR-32 cell lines compared to HeLa and MDA-MB-231 cell lines. The synthesized compounds also showed significant activity on MDA-MB-231 cancer cell line with IC of 9.