Fluoride Induces Toxic Effects on the A549 Pulmonary Cell Line at Non-cytotoxic Concentrations.

Fluoride is emitted into the air not only through gas emissions but also from volcanic ash, leading to contact via inhalation. Therefore, the objective of the present study was to evaluate the cellular and biochemical responses in the A549 cell line after exposure to NaF (sodium fluoride) concentrations lower than those previously used in other studies to determine the impact on the lung epithelium. A549 cells were exposed to different concentrations (0.

Ecological interactions and unique resource partitioning between dolphins in the ultraoligotrophic eastern Mediterranean Sea.

This study delves into the eco-dynamics of three dolphin species in the ultra-oligotrophic waters off the southern Israeli Mediterranean coast - two neritic: the common bottlenose dolphin (Tursiops truncatus) and the common dolphin (Delphinus delphis) and one pelagic: the striped dolphin (Stenella coeruleoalba). It utilizes compound-specific stable isotope analysis of individual amino acids to investigate carbon and nitrogen source variability and trophic positioning among the three species. Muscle samples from stranded individuals were analyzed for carbon (δC) and nitrogen (δN) isotopic ratios of amino acids, with ΔδN (Glutamate-Phenylalanine) acting as an indicator of relative trophic position.

Adjunctive aids for the detection of oral squamous cell carcinoma and oral potentially malignant disorders: A systematic review of systematic reviews.

This study presents the results of systematic reviews on adjunctive tools in screening and diagnosis of oral squamous cell carcinoma (OSCC) and oral potentially malignant disorders (OPMD) and to determine if the current literature supports their use as either an adjunctive tool or replacement of gold standard techniques. Systemic reviews and meta-analysis that evaluated adjunctive tools including chemiluminescence, tissue autofluorescence, tissue fluorescence spectroscopy, vital staining and cytology techniques were systematically examined using AMSTAR II. Twenty-seven systematic reviews were included.

Burning mouth disorder and Parkinson's disease: A scoping review of the literature.

Background: Burning mouth disorder (BMD) is a complex medical condition characterized by a burning sensation in the mouth of fluctuating intensity. BMD is considered a diagnosis of exclusion, as oral burning can occur secondary to local or systemic conditions. Parkinson's disease (PD) is one such condition.

The emergence of the circadian clock network in hiPSC-derived hepatocytes on chip.

The circadian clock has paramount implications in physiology and pathology. Although the circadian clock has been widely investigated in adults, up to now very little is known about how circadian rhythms emerge during embryonic development. Some studies about the ontology of the circadian system are focused on the development of the central pacemaker, whereas there is still no agreement about the development of the circadian clock in peripheral tissues.