Mitigating selection in HLA-B27 not confirmed.

The existence of a small, discrete group of HLA-B27 promoters, potentially able to mitigate the deleterious effect of this allele, has not been confirmed.

A semantic network model for the medical record of a rheumatology clinic.

For the development of a rheumatology information system, a medical data dictionary was developed that supports all phases of software development. In the design phase, the medical expert described his clinical environment and the rheumatology medical record in a semantic network structure. Causal relationships between different items of the medical record (e.