Early-onset group B (EOGBS) infection subsequent to cessation of screening-based intrapartum prophylaxis: findings of an observational study in West London, UK.

Objectives: To describe the impact on early-onset group B (EOGBS) infection rates following reversion from screening-based to risk-based intrapartum antimicrobial prophylaxis (IAP) for prevention.

Setting: Maternity services provided by secondary healthcare organisation in North West London.

Participants: All women who gave birth in the healthcare organisation between April 2016 and March 2017.

Outcome of a screening programme for the prevention of neonatal invasive early-onset group B Streptococcus infection in a UK maternity unit: an observational study.

Background: Against a background of failure to prevent neonatal invasive early-onset group B infections (GBS) in our maternity unit using risk-based approach for intrapartum antibiotic prophylaxis, we introduced an antenatal GBS carriage screening programme to identify additional women to target for prophylaxis.

Objectives: To describe the implementation and outcome of an antepartum screening programme for prevention of invasive early-onset GBS infection in a UK maternity unit.

Design: Observational study of outcome of screening programme (intervention) with comparison to historical controls (preintervention).