ANALYSIS OF IMMUNE CHANGES AND THEIR ROLE IN THE DEVELOPMENT OF ORAL AND OROPHARYNGEAL CANCER.

Numerous studies of the immune system in cancer patients at the cellular and molecular levels indicate a persistent violation of natural and acquired mechanisms of immune defense. This article reveals changes in the immune system of patients with cancer of the oral cavity and oropharynx. It was determined that the levels of cytokines IL-6, IL-10, HGF and VEGF in high concentrations in the serum of patients correlate with an unsatisfactory prognosis and are independent indicators of low survival and correlate with relapse.

[ASSESSMENT OF COMBINED PROPHYLAXIS OF PATHOLOGICAL POSTOPERATIVE FACE SKIN SCARS ACCORDING TO THE VANCOUVER SCALE].

The aim of the research was to study the effectiveness of combined prophylaxis of pathological postoperative face skin scars according to the Vancouver scale. The research involved 29 patients, aging 16-48 years old, who underwent maxillofacial surgery by extraoral accesses with wound primary intention healing. The patients were divided into three groups: the control group, which involved the patients, who after the surgery did not undergo any preventive measures to avoid pathological skin scars development, and two study groups.

[APPLICATION OF SYNTHETIC OSTEOPLASTIC MATERIAL EASYGRAFT® IN MAXILLA SUBANTRAL AUGMENTATION (SINUS-LIFT)].

The problem of complex dental rehabilitation of a patient after partial or complete teeth loss is an urgent issue for dental practice. The most of patients coming to dentist with to make dentures on dental implants after tooth loss in lateral part of maxilla are often observed with atrophy of the alveolar bone resulting in maxillary sinus (sinus Haymori) enlargement. Creating an additional space for dental implant placement in the maxilla is possible by performing a sinus lift (subantral maxilla augmentation) - artificially thickening the lower and outer wall of the maxillary sinus with usage of osteoplastic materials.

[JUSTIFICATION OF CHOICE OF THE POSITION OF THE REINFORCEMENT ELEMENT OF A GLASS-FIBER ADHESIVE TIRE BASED ON THE STUDY OF DIAGNOSTIC MODELS IN THE ARTICULATOR AND THE FOLLOWING PARALLELMETRIC RESEARCH].

The aim of the study was to develop the most optimal variant for placing the reinforcing element of a fiberglass splint with the mobility of the anterior teeth on the basis of a parallelometric study of the diagnostic models of the jaws depending on the type of occlusion and the degree of bone resorption. For the most optimal variant of the placement of the reinforcing element of the adhesive splint with orthognathic bite and deep incisal overlap, the front slope of the model was selected with the transfer of the reinforcing element of the adhesive splint onto the lingual surface. With direct, prognathic and progenic bite and bone resorption up to ¼ height (according to retrography data), the back slope of the model was selected with the placement of the reinforcing element of the adhesive splint on the vestibular surface of the lower jaw.