Publications by authors named "G N Sherman"
Bariatric surgery and alcohol and substance use: A case-control survey study.
Drug Alcohol Depend
February 2025
Purpose: Studies suggest alcohol and/or other substance misuse may develop after bariatric surgery (BS), but findings are not consistent or conclusive.
Procedures: This cross-sectional online survey investigated alcohol and other substance use, via a modified version of the Alcohol Use Disorders Identification Test, before and after bariatric surgery, compared to a non-bariatric surgery sample. Data were anonymously collected via Qualtrics from adults who reported alcohol or substance use (BS, n = 328; non-BS, n = 292).
BACKGROUNDStudies have demonstrated the role of ghrelin in alcohol-related behaviors and consumption. Blockade of the growth hormone secretagogue receptor (GHSR), which is the ghrelin receptor, has been shown to decrease alcohol drinking and reward-related behaviors across several animal models. We previously conducted a human study testing a GHSR inverse agonist/competitive antagonist, PF-5190457, in individuals who are heavy drinkers and showed its safety when coadministered with alcohol.
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- - This study investigates the impact of social protection, specifically government cash transfers and food security, on the health and well-being of adolescents living with HIV (ALHIV) in South Africa, focusing on achieving Global AIDS Targets like ART adherence, viral suppression, and reduced stigma.
- - Over four years, researchers collected data from 1,046 ALHIV, examining factors such as ART adherence, sexual behavior, and stigma, while using advanced regression models to analyze outcomes related to cash transfers and food security.
- - Results showed that receiving cash transfers and having food security were linked to better ART adherence and viral suppression, delayed sexual debut or consistent condom use, and lower enacted stigma among ALHIV, highlighting the importance of social support in
Background: Vaccine hesitancy is increasingly recognized as a health challenge affecting populations worldwide. Given the biological vulnerabilities and structural barriers people who use substances and/or have behavioral addictions face, this systematic review aims to evaluate whether this subpopulation is less prone to adhere to vaccination recommendations.
Methods: Electronic searches of published original research were conducted in PubMed, EMBASE, Scopus, and PsycINFO from database inception to December 2022.
Background: Valganciclovir is the only approved antiviral for cytomegalovirus (CMV) prevention in pediatric solid organ transplantation (SOT). Additional approaches may be needed to improve outcomes.
Methods: A multicenter retrospective study from 2016 to 2019 was conducted of pediatric SOT recipients in whom at least 3 months of valganciclovir prophylaxis was planned.