Association of an oversized adrenal cortical adenoma with expression of pheochromocytoma-like neurosecretory features.

Abnormal stimulation of adrenal function may be either direct, affecting similarly cortical and medullary secretion, or indirect affecting primarily the medulla. Indirect activation of clinically detectable adrenomedullary function may develop as a physical consequence of a non-functional adrenal tumor exerting pressure on the medulla by its size, location and direction of growth. Our case of an oversized and overweight adrenal tumor associated with expression of late-onset pheochromocytoma-like clinical symptoms may be explained by the physical indirect rather than the biological direct activation of adrenomedullary function like hyperplasia or cancer.

Multidisciplinary management of hepatocellular carcinoma.

Background/aims: The continuing poor prognosis for patients with hepatocellular carcinoma drives a search for new adjuvant therapies. Targeted locoregional immuno-chemotherapy is one of the most promising.

Materials And Methods: From 1990 to 1996, 193 patients who were not eligible for liver resection were treated in a prospective randomized study.

Intrahepatic cholangiojejunostomy in biliary stricture following resectional liver surgery.

Background: Biliary strictures after resectional liver surgery is a severe complication and remains a challenge. In this study we present our experience with intrahepatic cholangiojejunostomy (IHCJ) as the method of choice for the management of this complication.

Methods: Between September 1983 and January 1993, 115 IHCJs were performed.