Publications by authors named "G Moroncini"

Objectives: Gastroesophageal reflux disease (GERD) is frequent in systemic sclerosis (SSc) and could predict progression of interstitial lung disease (ILD). We aimed to analyse (1) the prevalence of GERD among SSc-ILD patients, (2) its association with disease characteristics and (3) predictive factors for ILD progression in SSc-ILD patients with GERD.

Methods: SSc patients from the EUSTAR database with ILD were included.

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Article Synopsis
  • - Gastrointestinal complications are common in systemic sclerosis (SSc) and may be linked to autoimmune factors and blood vessel damage, but the exact causes are unclear.
  • - The study examined the small blood vessels in the abdomen of SSc patients using Doppler Ultrasound to explore their relationship with GI symptoms and disease progression.
  • - Results showed differences in blood flow measurements between types of SSc and found significant correlations between blood vessel function and GI symptoms like fecal incontinence.
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Article Synopsis
  • * Curcumin has low absorption in the body but significantly interacts with gut microbiota, which is essential for overall health and plays a role in conditions like type 2 diabetes and metabolic syndrome.
  • * Restoring a healthy gut microbiome can improve blood sugar regulation and reduce insulin resistance, highlighting the potential of curcumin in managing metabolic disorders.
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Background: Increasing evidence supports the presence of cognitive impairment in patients with systemic sclerosis. Malnutrition is a well-known severe complication of systemic sclerosis and is a consequence of multiple factors, mainly oropharyngeal and gastrointestinal involvement. Recent studies have shown a link between nutrition and cognitive decline in several chronic diseases.

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