Molecular study of proteinuria in patients treated with B₁₂ supplements: do not forget megaloblastic anemia type 1.

Background/aims: Current consensus supports the notion that proteinuria is a marker of renal disease with prognostic implications. Whereas most chronic kidney disease patients with proteinuria would often require antiproteinuric agents, there are some exceptions. Megaloblastic anemia type 1 (MGA1) is characterized by megaloblastic anemia due to congenital selective vitamin B(12) malabsorption and proteinuria.

Circulating aggregated platelets, number of platelets per aggregate and platelet size in chronic dialysis patients.

The accelerated arteriosclerosis of chronic dialysis patients is multifactorial. Both non-uremic patients with atherosclerosis and uremic patients have functional platelet abnormalities. Our aim was to study platelet function in chronic dialysis patients and to correlate the findings with the presence of cardiovascular morbidity.

Hospitalizations in dialysis end-stage renal failure patients.

The cost of treating end-stage renal failure (ESRF) patients includes not only the cost of dialysis and related medications but also the cost of hospitalizing these patients. This study examines the hospitalization rate in ESRF patients. During 1993, 126 ESRF patients were dialyzed in our institution.

Sweat electrolytes in patients with advanced renal failure.

The sweat gland has some similarity with the convoluted tubules of the kidney. Little is known about sweat secretion and electrolyte content of sweat in the uremic gland. A pilocarpine ionotophoresis sweat test was performed in 40 patients with advanced renal failure (RF).