Publications by authors named "G Moores"
Fertility treatment, including assisted reproductive technology (ART), is increasingly used. Sex hormones influence seizure control as well as interacting with antiseizure medications, and so the hormonal manipulation involved in fertility treatments has direct implications for people with epilepsy. Here, we summarise the various fertility treatments and consider their important influences on epilepsy care.
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- Neurology research has historically favored male subjects, with a lack of reporting on sex differences; recent trends emphasize including more female participants and accurately assessing sex distinctions in studies.
- A scoping review from 2014 to 2020 analyzed literature on sex differences across four neurological subspecialties (demyelination, headache, stroke, epilepsy) and found that 585 relevant studies met the criteria, primarily observational and rarely random controlled trials.
- Despite the recognition of sex and gender as vital health factors, misapplication of these terms remains common, as 36% of articles used them interchangeably or incorrectly, indicating ongoing challenges in integrating these considerations into neuroscience research.
Article Synopsis
- The review focuses on the significance of sex and gender in neurology, addressing the historical male bias in research that limits female representation in clinical studies.
- It outlines a detailed methodology for analyzing peer-reviewed literature on sex differences in four neurological areas: demyelination, stroke, epilepsy, and headache, covering studies published from 2014 to 2020.
- The study aims to identify trends and gaps in current research to guide future investigation, with plans for dissemination through publication and presentations.