Publications by authors named "G Montalbano"

Polyvinyl butyral (PVB) is a high-performance thermoplastic polymer, commonly used as an interlayer material in laminated safety glass for the automotive and architectural sectors. Currently, there is no end-of-life cycle program for a substantial amount of PVB film, which mainly ends up in landfills. According to a circular approach, PVB can be revalorized after efficient separation and recovery from glass.

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Inner ear disorders, including sensorineural hearing loss, Meniere's disease, and vestibular neuritis, are prevalent conditions that significantly impact the quality of life. Despite their high incidence, the underlying pathophysiology of these disorders remains elusive, and current treatment options are often inadequate. Emerging evidence suggests that pericytes, a type of vascular mural cell specialized to maintain the integrity and function of the microvasculature, may play a crucial role in the development and progression of inner ear disorders.

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Article Synopsis
  • Mosaic variegated aneuploidy (MVA) is a rare genetic disorder characterized by aneuploidies, mainly involving multiple chromosomes, leading to a variety of health issues like growth delay and congenital abnormalities.
  • A case study of a patient revealed a unique form of MVA with specific trisomies (mainly involving chromosomes 18 and 19) that caused intermittent mild neutropenia without severe symptoms over more than 20 years.
  • Genetic testing for known mutations related to MVA, as well as whole exome analysis, failed to identify any causative mutations, highlighting the complexity and uniqueness of this patient's condition.
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Piezo proteins have been identified as mechanosensitive ion channels involved in mechanotransduction. Several ion channel dysfunctions may be associated with diseases (including deafness and pain); thus, studying them is critical to understand their role in mechanosensitive disorders and to establish new therapeutic strategies. The current study investigated for the first time the expression patterns of Piezo proteins in zebrafish octavolateralis mechanosensory organs.

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Bone tissue engineering (BTE) aims to promote bone regeneration by means of the synergistic effect of biomaterials, cells, and other factors, as potential alternative to conventional treatments for bone fractures. To this aim, a composite material was developed, based on collagen type I, strontium-enriched mesoporous bioactive glasses, and hydroxyapatite nanorods as bioactive and biomimetic components. Nanostructured scaffolds were 3D printed and subsequently chemically crosslinked with genipin to improve mechanical properties and stability.

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