Publications by authors named "G Moeller"
This paper focuses on the retrieval of refractivity fields from GNSS measurements by means of least-squares collocation. Collocation adjustment estimates parameters that relate delays and refractivity without relying on a grid. It contains functional and stochastic models that define the characteristics of the retrieved refractivity fields.
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- This study investigates the impact of chronic cocaine use on brain structure, specifically focusing on white matter microstructure using diffusion tensor imaging (DTI) technology.
- A total of 46 participants were involved—25 with a history of cocaine use disorder (CocUD) and 21 healthy controls—to analyze differences in DTI metrics.
- Results showed that cocaine users exhibited significant reductions in fractional anisotropy (FA) and axial diffusivity (AD) in various brain regions compared to controls, but the influence of lifetime alcohol use on these findings remains uncertain.
Drug addiction can lead to many health-related problems and social concerns. Researchers are interested in the association between long-term drug usage and abnormal functional connectivity. Functional connectivity obtained from functional magnetic resonance imaging data promotes a variety of fundamental understandings in such association.
View Article and Find Full Text PDFADP-ribosylation is a modification that targets a variety of macromolecules and regulates a diverse array of important cellular processes. ADP-ribosylation is catalysed by ADP-ribosyltransferases and reversed by ADP-ribosylhydrolases. Recently, an ADP-ribosyltransferase toxin termed 'DarT' from bacteria, which is distantly related to human PARPs, was shown to modify thymidine in single-stranded DNA in a sequence specific manner.
View Article and Find Full Text PDFObjectives: Evidence from genome-wide and candidate gene association studies, familial aggregation and linkage analyses demonstrate the genetic contribution to fibromyalgia (FM) disease. This study aimed to identify genetic biomarkers of FM and its related comorbid disorders, by exploring 41 polymorphisms potentially involved in FM pathogenesis in families with at least one patient with FM.
Methods: Core symptoms were assessed, and blood samples collected from 556 patients with FM and 395 healthy relatives.