STUDY OF PHYSICAL AND TECHNOLOGICAL FEATURES AND CHEMICAL COMPOSITION OF CLAYS PREVALENT IN ADJARA REGION.

The Region of Adjara is one of the most interesting region by existence of mineral resources, which is not only untapped also not studied. At this stage of study, our purpose was: to research physical features and a chemical composition of biologically active substances in the clays spread in Adjara. In particular, we determined the fractional content and particle size of samples, density, humidity, fluidity, Petrographic studies and X-ray diffraction, also existence of amino and fatty acids.

[Influence of Gentiana lutea L extract on blood coagulation].

The dry extract from the terrestrial parts of Gentiana Lutea was received in accordance to the developed by us general technological scheme. Study of the pharmacological influence of obtained extract on the coagulating properties of blood revealed that after its per os instillation into experimental animals the time of the formation of active thromboplastin reliably increases, while the time of thrombin and fibrinous cluster formation is shortened in comparison with those indices in the animals, that did not receive phyto-preparation, at the same time morphological appearance of the peripheral blood remains unchanged. Dry extract of terrestrial parts of Gentiana Lutea prepared in accordance to the technology recommended by us, together with widely known pharmacological effects, is characterized with new activity - influence on haemostasis.

[Development of the technology of the substance of davikol and standardization].

Among wide assortment of pharmaceutical remedies, that use modern medicine as a weapon against different diseases, special place belongs to the ophthalmic pharmaceutical forms, and their development presents independent branch of pharmaceutical technology. Recently, as a reason of various diseases and among them ophthalmic problems, is considered free radicals and reactions with their participation. Protection of the organism from such diseases presents a main goal of antioxidant system.

[Experimental investigation of general toxiology of antioxidant eyedrops davicol].

Authors examined the toxicity of antioxidant eye drops--davikoli. Antioxidants play important role in protecting the body from the formation of very dangerous substances referred to as free radicals. On the basis of honey an eye drops with high antioxidant activity--davicoli has been developed.