Post IVF heterotopic pregnancy with one in cervix and one in uterus. Successful delivery after termination of the cervical pregnancy with intraamniotic feticide.

Introduction: Cervical pregnancy is a rare kind of ectopic pregnancy. Heterotopic pregnancy is a condition, where we have one sac in the uterus and one in another location, usually because of IVF treatment. This scenario can become a life-threatening condition, if remain untreated.

Performance of International Ovarian Tumor Analysis (IOTA) predictive models in preoperative discrimination between benign and malignant adnexal lesions: preliminary outcomes in a Tertiary Care Hospital in Greece.

Objectives: To apply the International Ovarian Tumor Analysis (IOTA) predictive models, the logistic regression model 2 (LR2) and the IOTA Assessment of Different NEoplasias in the adneXa (ADNEX), in patients with ovarian masses and to compare their performance in preoperative discrimination between benign and malignant adnexal lesions.

Methods: This was a retrospective diagnostic accuracy study with prospectively collected data, performed between January 2019 and December 2022, in a single tertiary gynecologic oncology center in Greece. The study included women with an adnexal lesion which underwent surgery within 6 months after of using the LR2 and ADNEX protocol to assess the risk of malignancy.

Autophagy Blockage Up-Regulates HLA-Class-I Molecule Expression in Lung Cancer and Enhances Anti-PD-L1 Immunotherapy Efficacy.

Background/objectives: Immune checkpoint inhibitors have an established role in non-small cell lung cancer (NSCLC) therapy. The loss of HLA-class-I expression allows cancer cell evasion from immune surveillance, disease progression, and failure of immunotherapy. The restoration of HLA-class-I expression may prove to be a game-changer in current immunotherapy strategies.

Adenomatoid tumor of the fallopian tube: A case report and a review of the literature.

Introduction: Adenomatoid tumor is a rare, benign condition, more common in males, that affects the epididymis, spermatic cord and testicular tunics, whereas in females, the uterus and fallopian tubes. This solitary tumor is commonly appearing as an incidental finding. The diverse morphological characteristics of these tumors pose challenges in differential diagnoses.