Morbillivirus Canis Infection Induces Activation of Three Branches of Unfolded Protein Response, MAPK and Apoptosis.

, commonly named Canine distemper virus (CDV), is a morbillivirus implicated in several signs in the family. In dogs (), common signs of infection include conjunctivitis, digital hyperkeratosis and neuropathologies. Even with vaccination, the canine distemper disease persists worldwide so the molecular pathways implicated in the infection processes have been an interesting and promising area in new therapeutic drugs research in recent years.

Early life stress shifts critical periods and causes precocious visual cortex development.

The developing nervous system displays remarkable plasticity in response to sensory stimulation during critical periods of development. Critical periods may also increase the brain's vulnerability to adverse experiences. Here we show that early-life stress (ELS) in mice shifts the timing of critical periods in the visual cortex.

Alcohol Use and Abuse Among Family Caregivers of People Living with Dementia in the United States: A Scoping Review.

The population of the United States is rapidly aging due to a number of factors, such as lower fertility rates and increases in life expectancy. Globally, dementia is a leading cause of disability among older adults, affecting approximately 50 million people. Family caregivers, who often have to sacrifice their health and well-being, provide most of the care needed by older adults living with dementia.

Evaluating a German learning disorders platform using the RE-AIM framework.

In recent years, online platforms have made educational, medical, and other professional content easily accessible, but research evaluating such platforms is still scarce. The purpose of the current study is to evaluate LONDI, a German learning disorders platform. The platform offers scientifically based information for different user groups, and an algorithm-based help system that professionals can use to facilitate diagnosing and planning interventions.