Prenatal dance activity enhances foetal and postnatal cognitive and motor development.

Introduction: No research has examined the impact of any physical-artistic-cognitive activity on foetal neurodevelopment. The aim of the study was to investigate the efficacy of a unique prenatal dance activity in pre- and postnatal cognitive and motor development as a complementary health care practice.

Methods: 26 clinically uncomplicated primiparas and multiparas with singleton pregnancies and their later born children were examined in this prospective study at the University of Pécs, Hungary.

Structure-activity relationships of new muscarinergic dibenzodioxazocines.

1H-NMR and X-ray conformation studies of new muscarinergic dibenzodioxazocines have been carried out. It is suggested that EGYT-2347 (2-chloro-12-/2-piperidino-ethyl/-dibenzo [d,g] [1, 3, 6] dioxazocine hydrochloride) may exist in solution in at least two distinct conformations, unlike other tricyclic or non-tricyclic compounds having antimuscarinergic activity. One of these conformations possessing an asymmetric, twisted central hetero-ring confined between two phenyl rings is probably the energetically more stable form, while the other having a butterfly-like structure, with mirror symmetry-related phenyl rings as in phenothiazines seems to be more suitable for receptor binding.

Characteristic sequential residue environment of amino acids in proteins.

The occurrence of all di- and tripeptide segments of proteins was counted in a large data base containing about 119 000 residues. It was found that the abundance of the amino acids does not determine the frequency of the various di- and tripeptide segments. In addition, the frequency of the various tripeptides cannot be predicted from the observed pair-frequency values.

Kinetic pathways of formation and dissociation of the glycerol-3-phosphate dehydrogenase-fructose-1,6-bisphosphate aldolase complex.

Quantitative analysis of the time courses of fluorescence anisotropy changes due to the binding of fructose-1,6-bisphosphate aldolase to the dissociable cytoplasmic glycerol-3-phosphate dehydrogenase covalently labelled with fluorescent dye was carried out. The behaviour of the aldolase-dehydrogenase system seems to be consistent with a cyclic reversible model characterized by the formation and dissociation of complexes of both the monomeric and the dimeric forms of dehydrogenase with aldolase, and rapid equilibrium between the free monomeric and dimeric forms of dehydrogenase. The half-life time of the formation of dimeric dehydrogenase-aldolase complex at the concentration of the enzymes expected to exist in the cell (i.

Homologous partial sequences in dehydrogenases.

Such details of the primary structure were sought that are common in all dehydrogenases of known amino acid sequence. Twenty-six sequences of eight kinds of dehydrogenase (D-glyceraldehyde-3-phosphate dehydrogenase, alcohol dehydrogenase, lactate dehydrogenase, glutamate dehydrogenase, glycerol-3-phosphate dehydrogenase, ribitol dehydrogenase, L-hydroxyacyl-CoA dehydrogenase and homoserine dehydrogenase) have been compared by the aid of the artificial intelligence language Prolog, the amino acids being classified into groups according to their chemical properties, and alpha-helix or beta-sheet-forming abilities. We found tetrapeptides that occurred in all dehydrogenases examined.