The role of dual-energy computed tomography (DECT) in emergency radiology: a visual guide to advanced diagnostics.

Dual-energy computed tomography (DECT) has become an essential tool in emergency radiology, significantly enhancing diagnostic capabilities for a variety of acute conditions. By utilising two distinct X-ray energy spectra, DECT differentiates materials based on their attenuation properties, providing detailed insights into tissue composition and pathology. In emergency settings, DECT is used in thoracic imaging for the detection of pulmonary embolism, in abdominal imaging to enhance the diagnosis and characterisation of conditions such as pancreatitis, appendicitis, gastrointestinal bleeding, and bowel ischaemia and in the genitourinary system for identifying kidney stones, pyelonephritis, and urinary bleeding.

AKT and EZH2 inhibitors kill TNBCs by hijacking mechanisms of involution.

Triple-negative breast cancer (TNBC) is the most aggressive breast cancer subtype and has the highest rate of recurrence. The predominant standard of care for advanced TNBC is systemic chemotherapy with or without immunotherapy; however, responses are typically short lived. Thus, there is an urgent need to develop more effective treatments.

The Role of Artificial Intelligence and Texture Analysis in Interventional Radiological Treatments of Liver Masses: A Narrative Review.

Liver lesions, including both benign and malignant tumors, pose significant challenges in interventional radiological treatment planning and prognostication. The emerging field of artificial intelligence (AI) and its integration with texture analysis techniques have shown promising potential in predicting treatment outcomes, enhancing precision, and aiding clinical decision-making. This comprehensive review aims to summarize the current state-of-the-art research on the application of AI and texture analysis in determining treatment response, recurrence rates, and overall survival outcomes for patients undergoing interventional radiological treatment for liver lesions.

Ultrasound-assisted dispersive solid-liquid microextraction with eutectic solvents for the determination of cannabinoids in different hemp products.

The wide range of applications of hemp products, together with the environmental benefits that come from hemp cultivation are driving up the market demand for Cannabis sativa L. plant. One of the main restrictions for hemp cultivation and marketing concerns the content of delta-9-tetrahydrocannabidiol (Δ-THC), which is known to have psychotomimetic effect.

New Class of Tunable Choline Bromide-Based Hydrophobic Deep Eutectic Solvents for the Extraction of Bioactive Compounds of Varying Polarity from a Plant Matrix.

Deep eutectic solvents (DESs) are a class of sustainable solvents that have found numerous applications in different fields. One of their main attributes is the possibility of easily modifying their physicochemical properties by varying the type of hydrogen bond donor (HBD) and hydrogen bond acceptor (HBA) that comprise them. Choline chloride ([Ch][Cl])-based hydrophilic DESs were among the first studied and the most used because of their capacity to easily create a hydrogen bonding network that lies in its unique chemical structure, characterized by a hydroxyl substituent within the ammonium headgroup.