Publications by authors named "G Mastella"

Article Synopsis
  • The study explores how alcohol consumption during pregnancy affects the development of schizophrenia-like behaviors in rat offspring, linking intrauterine factors to adult mental health outcomes.
  • Pregnant Wistar rats were given either alcohol or water, and their offspring underwent various behavioral tests and biochemical analyses at different ages to assess the impacts of prenatal alcohol exposure and subsequent ketamine injections.
  • Results showed that alcohol exposure led to increased hyperactivity and cognitive impairments, particularly in male offspring, indicating that early stressors can have lasting effects on behavior and brain chemistry, potentially increasing vulnerability to additional stressors later in life.
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Laboratory acoustic emissions (AEs) serve as small-scale analogues to earthquakes, offering fundamental insights into seismic processes. To ensure accurate physical interpretations of AEs, rigorous calibration of the acoustic system is essential. In this paper, we present an empirical calibration technique that quantifies sensor response, instrumentation effects, and path characteristics into a single entity termed instrument apparatus response.

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Aims: Pulmonary vein isolation (PVI) represents the gold standard in the treatment of atrial fibrillation (AF) and the use of single-shot techniques, such as cryoballoon ablation (CBA) and pulsed field ablation (PFA) using a pentaspline catheter, has gained prominence. Recent studies hypothesize that PFA might be superior to CBA, although procedural efficacy and safety data are inconsistent. A meta-analysis was conducted to compare both energy sources for the treatment of AF.

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Introduction: Today, modern technology is used to diagnose and treat cardiovascular disease. These medical devices provide exact measures and raw data such as imaging data or biosignals. So far, the Broad Integration of These Health Data into Hospital Information Technology Structures-Especially in Germany-is Lacking, and if data integration takes place, only non-Evaluable Findings are Usually Integrated into the Hospital Information Technology Structures.

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Many aspects of the impact of childhood trauma remain unknown, such as the age at which individuals are most vulnerable to trauma, whether traumatic experiences have more severe and lasting effects when experienced early in life, and whether early life trauma causes psychiatric conditions such as anxiety and major depressive disorder (MDD) that persist over time or evolve into other disorders. Thus, this study aimed to investigate the impact of traumatic experiences in childhood on susceptibility to mood disorders in adulthood, particularly MDD. Animal models were used to address these questions, and different stressor protocols at various stages of the offspring's life were used.

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