Publications by authors named "G Masko"

Background: Locoregional failure after breast cancer treatment is usually heralded as a significant risk factor for systemic recurrence. However, locoregional recurrence may have different presentations, some of which may represent a more benign course. An example of this is the phenomenon of isolated chest wall recurrence (CWR).

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Background: The objective of this study was to determine if standard tangential breast radiation covered the sentinel lymph node in women with invasive breast cancer.

Methods: Women with invasive breast cancer treated by lumpectomy, radiotherapy and sentinel node biopsy at our institution were included in this study if the sentinel lymph node site had been marked with a clip. Plain films were used to determine if the clip fell within the tangential fields.

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Article Synopsis
  • The study followed 62 patients with advanced squamous cell carcinoma of the upper aero-digestive tract who received either conventional or accelerated radiotherapy between 1980 and 1988.
  • Patients treated with accelerated superfractionation showed significantly better local tumor control rates (67% vs. 40%) and disease-free survival (64% vs. 40%) compared to those who received conventional daily radiotherapy.
  • No major differences in acute treatment toxicity were noted between the two groups, suggesting that the accelerated regimen not only improved outcomes but did so safely.
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