Publications by authors named "G Mascioli"

Article Synopsis
  • The study explored how changes in QRS index (QI) after cardiac resynchronization therapy (CRT) relate to patient outcomes and prognosis.
  • Significant improvements in cardiac function were observed within six months, with a specific QI cut-off value predicting better reverse remodeling in heart structure.
  • Higher QI values indicated lower rates of adverse events and a better ability to predict CRT responses, highlighting its potential clinical significance.
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Article Synopsis
  • Cardiac pacing traditionally focused on stimulating the right ventricle to address conduction issues, but recent advancements have shifted attention to preventing pacing-induced dyssynchrony through cardiac resynchronization.
  • Studies indicate that conduction system pacing (CSP), particularly techniques like His bundle stimulation and left bundle branch pacing, not only prevent dyssynchrony but also effectively address conduction blocks with better outcomes than biventricular pacing.
  • Despite promising findings, the European Society of Cardiology guidelines currently recognize CSP's role only minimally, highlighting a gap between emerging practices and official recommendations.
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Superior vena cava (SVC) syndrome is a rare disease induced by thrombosis and consequent occlusion of SVC, negatively affecting morbidity and mortality. The incidence of SVC syndrome from central venous catheters and pacemaker or defibrillator leads is increasing. Optimal treatment of pacemaker or defibrillator-related SVC syndrome is not well defined.

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Implantation of pacemakers and cardiac defibrillators is a life-saving treatment but can put our patients at risk of infections, increasing morbidity and mortality and prolonging hospitalization with a significant financial healthcare burden. A preventive strategy is crucial but, while several strategies such as administration of intravenous antibiotic therapy before implantation are well recognized, other uncertainties remain. The main gaps regard the use of periprocedural measures, including antibacterial envelope to prevent device infection, the appropriate management of antithrombotic therapy before and after device implantation and timing of device reimplantation.

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Aims: The coronavirus disease-19 (COVID-19) outbreak has been recently associated with lower hospitalization rates for acute coronary syndromes. Aim of the study was to investigate whether a similar behaviour is observed in admissions for urgent pacemaker implant.

Methods: This retrospective study included 1315 patients from 18 hospitals in Northern Italy with a high number of COVID-19 cases.

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