Publications by authors named "G Martemucci"
Several hallmarks of metabolic syndrome, such as dysregulation in the glucose and lipid metabolism, endothelial dysfunction, insulin resistance, low-to-medium systemic inflammation, and intestinal microbiota dysbiosis, represent a pathological bridge between metabolic syndrome and diabesity, cardiovascular, and neurodegenerative disorders. This review aims to highlight some therapeutic strategies against metabolic syndrome involving integrative approaches to improve lifestyle and daily diet. The beneficial effects of foods containing antioxidant polyphenols, intestinal microbiota control, and physical activity were also considered.
View Article and Find Full Text PDFResponse of laying hens fed diet supplemented with a mixture of olive, laurel, and rosemary leaf powders: Metabolic profile, oxidative status, intestinal histomorphology, and egg quality.
Res Vet Sci
July 2024
Article Synopsis
- The study investigated the impact of a leaf powder mixture (olive, laurel, and rosemary) on various health and egg quality parameters in Lohmann Brown hens.
- The mixture improved oxidative status, immune response, and biochemical indicators like total protein and HDL cholesterol, while also reducing total and LDL cholesterol levels.
- There were significant improvements in intestinal health, with increased short chain fatty acids and better gut morphology, but egg quality remained unchanged.
Article Synopsis
- * Key factors associated with MS include oxidative stress, insulin resistance, abdominal obesity, and hypertension, leading to complications like diabesity and cardiovascular diseases.
- * Understanding the connections between MS and these related health problems can help develop strategies to reduce the negative impacts and comorbidities of metabolic syndrome.
Excessive and uncontrolled oxidative stress can damage biomacromolecules, such as lipids, proteins, carbohydrates, and DNA, by free radical and oxidant overproduction. In this review, we critically discuss the main properties of free radicals, their implications in oxidative stress, and specific pathological conditions. In clinical medicine, oxidative stress can play a role in several chronic noncommunicable diseases, such as diabetes mellitus, cardiovascular, inflammatory, neurodegenerative diseases, and tumours.
View Article and Find Full Text PDFArticle Synopsis
- Aging involves a gradual decline in tissue and organ function influenced by genetics, environment, nutrition, and lifestyle, with oxidative stress playing a key role in cellular aging and frailty.
- Several factors contribute to aging, including genomic instability, telomere shortening, and mitochondrial dysfunction, all of which can be affected by diet and lifestyle choices.
- Nutritional strategies such as the Mediterranean diet, dietary antioxidants, and caloric restriction show potential for promoting healthy aging and could lead to new biomarkers and treatments aimed at extending lifespan.