Publications by authors named "G Mark Richardson"
This study investigates why individuals with multimorbidity-two or more chronic conditions-are more prone to adverse outcomes after surgery. In our cohort, ninety-eight of 144 participants had multimorbidity. The myocardial transcriptome and metabolites involved in energy production were measured in 53 and 57 sequential participants, respectively.
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- * Key features of neurodegenerative diseases include mitochondrial dysfunction, oxidative stress, and protein aggregation, particularly affecting dopaminergic neurons, which are crucial in PD progression.
- * The review explores how disruptions in NPCs, nuclear transport, and the nuclear envelope may contribute to PD, emphasizing the need for further research on how these mechanisms interact with oxidative stress in the disease.
A drift-diffusion model is used to investigate the effect of device degradation on current-voltage and impedance measurements of perovskite solar cells (PSCs). Modifications are made to the open-source drift-diffusion software IonMonger to model degradation via an increasing recombination rate during the course of characterization experiments. Impedance spectroscopy is shown to be a significantly more sensitive measure of degradation than current-voltage curves, reliably detecting a power conversion efficiency drop of as little as 0.
View Article and Find Full Text PDFThe antiviral drug tecovirimat* has been used extensively to treat U.S. mpox cases since the start of a global outbreak in 2022.
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