Publications by authors named "G Margiotta"
Fertility preservation in lymphoma patients treated with immunochemotherapy regimens with or without radiotherapy: results of a retrospective multicenter Italian study (Ferty care).
Leuk Lymphoma
October 2024
Article Synopsis
- - The study examined fertility preservation methods in 414 female lymphoma patients aged 18-40 diagnosed between 2010 and 2018, with most common cancer types being Hodgkin Lymphoma (74%) and various others.
- - Majority of the patients (71%) received ABVD as the first-line treatment, while fertility preservation strategies included GnRHa (78%), oral contraceptives, and cryopreservation of oocytes and ovarian tissue.
- - After treatment, 70% of women had regular menstrual cycles, 8% experienced premature ovarian failure, and there were 43 pregnancies observed during a median follow-up of 5 years, with age and treatment intensity being significant factors for amenorrhea and POF.
Objective: Despite having normal thyroid-stimulating hormone levels, many hypothyroid patients are dissatisfied with the treatment. The primary aim of this study was to evaluate the effect of twice-daily, combination therapy with levothyroxine (LT4) and liothyronine (LT3), at doses adapted according to TSH-level, on peripheral tissues as reflected by sex hormone binding globulin (SHBG) levels in totally thyroidectomized patients. Changes in other tissue markers and quality of life considering DIO2-rs225014 and MCT10-rs17606253 genetic variants were also assessed.
View Article and Find Full Text PDFFeeding, eating and deglutition difficulties are key concerns in patients with cardiofaciocutaneous syndrome (CFCS). This study intends to quantify the development of feeding skills from birth to adulthood in patients with CFCS. Twenty-seven patients (eight males; mean age: 16.
View Article and Find Full Text PDFArticle Synopsis
- Acrodermatitis enteropathica is a rare condition marked by dermatitis, hair loss, and diarrhea, often linked to zinc deficiency, which can occur due to poor diet or complications from parenteral nutrition.
- A 5-year-old child who had been on total parenteral nutrition for a month developed symptoms including skin lesions and extremely low zinc levels, which were found after a challenging diagnosis due to other existing health issues.
- After starting zinc supplementation, the child's condition improved rapidly, highlighting the importance of trace elements in parenteral nutrition and the need to consider acrodermatitis enteropathica in similar cases.