Publications by authors named "G Marchesini"

This work is the third in a series of articles dedicated to the EASY-NET network programme. The first article described the rationale, structure, and methodologies; while the second evaluated the adherence of individual audit&feedback A&F interventions tested in EASY-NET to literature recommendations. This contribution provides a concise summary of the effectiveness results of A&ented by clinical and organizational areas: chronic disease management, emergency territorial and hospital care for acute conditions, post-acute rehabilitation, hospital oncology care, childbirth, and caesarean sections.

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Article Synopsis
  • Recent international guidelines have defined metabolic dysfunction-associated steatotic liver disease (MASLD), leading to a rise in its prevalence as a reason for liver transplantation (LT) in Italy between 2012 and 2022.
  • * An analysis of 1,941 patients with MASLD and 11,201 without MASLD revealed that while the prevalence of MASLD patients waiting for LT increased significantly, it did not independently affect patient survival post-transplant.
  • * Patients with non-HCC MASLD faced higher mortality rates on the waiting list but projected better 5-year transplant survival benefits than those without MASLD or HCC.
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Near infrared spectroscopy (NIRS) is an analytical technique that offers a real advantage over laboratory analysis in the food industry due to its low operating costs, rapid analysis, and non-destructive sampling technique. Numerous studies have shown the relevance of NIR spectra analysis for assessing certain food properties with the right calibration. This makes it useful in quality control and in the continuous monitoring of food processing.

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Article Synopsis
  • The FDA approved resmetirom as the first drug for treating non-alcoholic steatohepatitis (NASH) with fibrosis on March 14, 2024, after over 25 years of research and challenges.
  • The drug is intended to work alongside lifestyle changes, which have been the only approved treatment for this condition until now.
  • Important questions arise about trial continuation, appropriate community use, managing coexisting health issues, and ensuring cost-effectiveness to avoid disparities in treatment access.
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Aims: To assess the effectiveness of the intermittent-scanned continuous glucose monitoring (isCGM) system in preventing severe hypoglycemic episodes and in improving glucose parameters and quality of life.

Methods: Four hundred T1D individuals were enrolled in a prospective real-word study with an intermittently scanned continuous glucose monitoring device during the 12-months follow-up. The primary endpoint was the incidence of severe hypoglycemic events.

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