Publications by authors named "G Marcelo"

Article Synopsis
  • Mechanochemistry and photocatalysis are innovative approaches for breaking down polycyclic aromatic hydrocarbons (PAHs) like pyrene in soils.
  • The study investigates how applying pressure to pyrene and sepiolite enhances its degradation through a combined mechanism, facilitating a crystal phase transformation that accelerates photodegradation.
  • The findings suggest that sepiolite is more effective than traditional photocatalysts like TiO when it comes to degrading pyrene, providing insights into the processes of PAH degradation in soil environments.
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Article Synopsis
  • β-cyclodextrin (βCyD) derivatives with aromatic appendages can self-assemble and respond to stimuli, making them useful for applications like nonviral gene delivery systems.
  • A particular azobenzene moiety can be attached to βCyD to create derivatives that form light-regulated dimers, allowing for controlled organization through photoswitching.
  • The study utilizes various techniques to analyze these interactions and the stability of the supramolecular structures, highlighting their potential for advanced applications in materials science and biotechnology.
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The need for non-invasive therapies capable of conserving drug efficiency and stability while having specific targetability against colorectal cancer (CRC), has made nanoparticles preferable vehicles and principal building blocks for the development of complex and multi-action anti-tumoral approaches. For that purpose, we herein report the production of a combinatory anti-tumoral nanotherapy using the production of a new targeting towards CRC lines. To do so, Magneto-fluorescent NANO3 nanoparticles were used as nanocarriers for a combination of the drugs doxorubicin (DOX) and ofloxacin (OFLO).

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Cancer-related opportunistic bacterial infections are one major barrier for successful clinical therapies, often correlated to the production of genotoxic factors and higher cancer incidence. Although dual anticancer and antimicrobial therapies are a growing therapeutic fashion, they still fall short when it comes to specific delivery and local action in in vivo systems. Nanoparticles are seen as potential therapeutic vectors, be it by means of their intrinsic antibacterial properties and effective delivery capacity, or by means of their repeatedly reported modulation and maneuverability.

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The rising of multidrug-resistant bacteria and their associated proliferation as harmful microorganisms boosts the creation of new antibacterial surfaces and biomaterials with applications ranging from health to food packing. Herein, low-cost antibacterial PVA:PVP copolymers containing cyanine derivatives (1, 2, and 3) and their respective Cu complexes are successfully obtained and tested against Gram-negative and Gram-positive bacteria. The possible application in food packing is addressed by covering the surface of typical paper mockups with the doped polymers.

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