Publications by authors named "G Makharia"
Introduction: Acute and chronic pancreatitis (CP) are inflammatory conditions of the pancreas that cause local and systemic complications. The epidemiology of these conditions are not well-known in India.
Methods And Analysis: We describe the protocol and procedures of a multicentre study for delineating the epidemiology of pancreatitis in India.
Article Synopsis
- First-degree relatives (FDRs) of celiac disease (CeD) patients are at a higher risk of developing the condition, with a systematic review analyzing the prevalence and symptoms using the anti-tissue transglutaminase antibody test.
- From 34 studies involving over 10,000 FDRs, the research found a seroprevalence of 11% and a biopsy-confirmed prevalence of 7%, with daughters and sisters showing the highest rates.
- The study suggests that about 1 in 14 FDRs may have CeD, emphasizing the need for routine screening to aid in early detection and management of the disease.
Article Synopsis
- Non-responsive celiac disease (NRCD) occurs when patients experience ongoing symptoms despite following a gluten-free diet for 6-12 months, with a prevalence found to be about 22% in a systematic review of studies.
- The analysis identified inadvertent gluten exposure as the leading cause of NRCD, affecting one-third of the patients, followed by functional gastrointestinal disorders like irritable bowel syndrome.
- The findings highlight the need for better adherence to gluten-free diets and the development of new treatments to address symptoms persisting from unintentional gluten intake.
Background And Aim: Celiac disease (CeD) is increasingly diagnosed but significant disparities exist in awareness, practices, resources, and legislation worldwide. We conducted a global online survey with CeD experts to assess this disparity internationally.
Methods: A 55 questions survey encompassing nine domains relevant to CeD care (awareness, gluten-free [GF] foods availability/cost/quality, GF labeling, CeD dietician availability, insurance for CeD patients, medical training, research funding, patient support groups, and unmet needs) was generated and sent to CeD experts worldwide electronically.