Publications by authors named "G Mahay"

Purpose: This review aimed to summarise evidence about the impact of pharmacological and non-pharmacological interventions on survival in COPD patients.

Methods: We performed a narrative literature review on the effect of pharmacological and non-pharmacological interventions on survival in COPD patients.

Results: Inhaled therapies are central to reduce symptoms in COPD.

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Article Synopsis
  • Asthma is a complex disease influenced by various factors, with ongoing research improving understanding of its inflammatory and immune mechanisms, leading to more targeted treatments.
  • Predictive markers for asthma severity include obesity, nasal polyposis, and functional measures like bronchial obstruction and high levels of FeNO, which can inform therapeutic responses.
  • Patients with severe asthma may benefit from specific biological therapies based on markers like elevated eosinophil counts and IgE levels, highlighting the importance of tailored approaches and considering environmental triggers for better management.
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Background: Dupilumab is a monoclonal anti-IL-4Rα antibody developed for the treatment of severe asthma (SA). An early access programme for dupilumab was opened in France in SA patients experiencing unacceptable steroids side-effects and/or life-threatening exacerbations.

Objective: To assess changes in asthma control between baseline and 12 months of treatment.

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